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In comparison to conventional metoprolol, the plasma metoprolol levels following administration of metoprolol succinate extended-release tablet are characterized by lower peaks, longer time to peak and significantly lower peak to trough variation.

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Metoprolol tartrate has been associated with reversible adverse effects on spermatogenesis starting at oral dose levels of 3.

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In 1969, metoprolol was made for the first time.

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Metoprolol tartrate tablets are indicated in the treatment of hemodynamically stable patients with definite or suspected acute myocardial infarction to reduce cardiovascular mortality when used alone or in conjunction with intravenous metoprolol tartrate.

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Jun 24, 2014 generic versions of toprol xl , a heart drug , are recalled.

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thus, this trial extends the time over which carvedilol manifests benefits on survival in heart failure, but it is not evidence that carvedilol improves outcome over the formulation of metoprolol toprol-xl with benefits in heart failure.

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